Michael Grome

Assistant Professor, Plant Biology
Lab:
MPS 4501
Office:
MPS 4611
Office Hours:
Thurs 3:30PM - 5:00PM
Research Interests:

Adapting microbial tools of translation engineering and genetic code expansion to plants for biologically safeguarded biomanufacturing, ncAA-protein engineering, and adaptive plant synthetic biology.

Selected Publications:

Grome, M.W., Nguyen, M.T.A., Moonan, D.W. et al. Engineering a genomically recoded organism with one stop codon. Nature (2025). https://doi.org/10.1038/s41586-024-08501-x

“GENOMICALLY RECODED ORGANISMS AND METHODS OF USING THE SAME”
Farren Isaacs, Jesse Rinehart, Michael William Grome, and Kyle Mohler U.S. Application No. 63/663,593 filed June 24, 2024

Grome MW, Isaacs FJ. 2021. ZTCG: Viruses expand the genetic alphabet. Science. 372 (6541):460-461

Shen Q, Grome MW, Yang Y, Lin C. 2019. Engineering Lipid Membranes with Programmable DNA Nanostructures. Advanced Biosystems. 4 (1), 1900215

Grome MW, Zhang Z, Lin C. 2019. Stiffness and Membrane Anchor Density Modulate DNA-Nanospring-Induced Vesicle Tubulation. ACS Appl. Mater. Interfaces. 22987-22992

Grome MW, Zhang Z, Pincet F, Lin C. 2018. Vesicle tubulation with self-assembling DNA nanosprings. Angewandte chemie. 57(19):5330-5334

Rovner AJ, Haimovich AD, Katz SR, Li Z, Grome MW, Gassaway BM, Amiram M, Patel JR, Gallagher RR, Rinehart J, Isaacs FJ. 2015. Recoded organisms engineered to be dependent on synthetic amino acids. Nature. 518, 89-93

Education:

Ph.D. Cellular Biology - Yale University '19 (specialty: DNA Nanotechnology)
M.A. Cellular Biology - Yale University '15
B.A. Plant Sciences - Cornell University '13 (specialty: Biotechnology)
B.A. Natural Resource Management - Cornell University '13

Of note:

Tom & Joan Steitz RNA Fellow - Yale University